EOSC4Cancer’s five use cases in WP5 cover the patient’s trajectory from cancer prevention, diagnosis, treatment, and medical management:

• Cancer risk identification and prevention by linking environmental data to cancer registry data
• Data-driven optimisation of cancer screening programmes
• Data-driven treatment selection for localised tumours with multiple patient-derived data types
• Data-driven treatment selection for localised tumour: improving the treatment of colorectal cancer by the inclusion of circulating DNA information
• Connecting omics data from multiple sources to a Clinical Decision Support System (CDSS) for precision treatment of metastatic colorectal cancer

Every step of the patient’s encounter with the use cases leaves a trail of data. These data are systematically organised and made relevant for use in translational research, medical practice, and health outcomes. We have chosen colorectal cancer as a working case for representing a tumour type with abundant data and ample cross border collaborations.

EOSC4Cancer sustains a robust infrastructure for knowledge and data bases. Accessibility, integration, and analysis of data across borders among researchers and healthcare professionals will leverage progress in health outcomes.

Cancer has a very complex nature and requires advanced and updated knowledge and practice rooted in strong medical research (evidence-based medicine). Hence, with high-quality cancer data across Europe, more efficient biological and technical innovations will reach the citizens of the EU.